Ultrafiltration

Ultrafiltration

Afferent arteriole which supplies oxygenated blood to our hephrom is wider in diameter as compared to efferent arteriole.

In the afferent Artriole, B. P is high as compared to efferent arteriole because it is regularly pumped by the heart. Hence in the glomerulus blood accumulates it develops a pressure on the wall of glomerulus due to which blood faltered.
During filtration Copillary endothelium and its basement membrane squamous epi & its.

Basement membrane forms Ultrafilter though which blood is filtered out. The filtered blood is called nephrie filtered or Ultrafiltration and this pressure is called Ultrafiltration.

Development of filtration pressure in the glomerulus :—

In the glomerulus capillary as teried B. P is 75mmHg.This pressure is resisted by the Osmotic substance which is present in blood. These Osmotic substance are Osmotic proteins.

Glomerulus asteriol pressure is also resisted by the fluid present in capsular space and in renal tubule. These fluid develops approx 10mmHg pressure each. Hence total 50mmHg pressure develops in the system to resist the asteriol B. P

        [ GFP=25mmHg ]

A/C to Goyton & Hall the glomesvlar B. P is 60mmHg which is resisted by the O. P of blood copsular fluid pressure & in terstinal fluid pressure balance.
A/C to Guyton & Hall, GFP is 60 = 10mmHg.

:— About 1100 to 1200 ml. Of blood enter in our two kidney per minute. Hence within 4—5 minutes whole blood of our body enters in kidney for filtration.

:— Approx 15—25 % of blood plasma filters our pre minute.

:— At this rote it filtration occurs then approx 125ml/ minute nephric Filtrate.

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